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Chronic Venous Ulcers – Autologous

We are recruiting patients with chronic venous ulcers (CVU) for a multicentric phase I/IIa clinical trial.

The aim of the trial is to examine the efficacy and safety of autologous ABCB5-positive mesenchymal stem cells (ABCB5+ MSCs) in patients with CVU. Primary endpoints are the percentage of wound size reduction and the occurrence of adverse events.

For this trial 37 patients will be recruited at two sites in Germany.

For the manufacturing process of the autologous ABCB5+ MSCs we are using a patent hold by the Brigham and Women’s Hospital, Boston/USA, and the Children’s Hospital, Boston/USA, in cooperation with our scientific partner Prof. Dr. Markus Frank.

More information about the trial can be found HERE (ClinicalTrials.gov) or HERE (EU Clinical Trials Register).

Background information about the use of ABCB5+ MSCs in CVU can be found HERE.

Study Centers

If you are interested, please contact the corresponding center.

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