Chronic Venous Ulcers – Autologous
We are recruiting patients with chronic venous ulcers (CVU) for a multicentric phase I/IIa clinical trial.
The aim of the trial is to examine the efficacy and safety of autologous ABCB5-positive mesenchymal stem cells (ABCB5+ MSCs) in patients with CVU. Primary endpoints are the percentage of wound size reduction and the occurrence of adverse events.
For this trial 37 patients will be recruited at two sites in Germany.
For the manufacturing process of the autologous ABCB5+ MSCs we are using a patent hold by the Brigham and Women’s Hospital, Boston/USA, and the Children’s Hospital, Boston/USA, in cooperation with our scientific partner Prof. Dr. Markus Frank.
Background information about the use of ABCB5+ MSCs in CVU can be found HERE.
Study CentersIf you are interested, please contact the corresponding center.
- Würzburg: Department of dermatology, venereology and allergology, Dermatological Study Center, University Hospital Würzburg
- Bochum: Phlebological Study Center at the vein center of the dermatological and vascular surgery clinics, in Bochum, open CVU flyer